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Image Search Results
Journal: Cell Reports Medicine
Article Title: Predictive models of response to neoadjuvant chemotherapy in muscle-invasive bladder cancer using nuclear morphology and tissue architecture
doi: 10.1016/j.xcrm.2021.100382
Figure Lengend Snippet: Diagram of computational framework The framework is initiated by tissue microarrays (TMAs) construction and image generation. Next, image preprocessing calibrates stain vectors for each TMA and then an area-variation-based criteria was adapted to select qualified cores for computational analysis. Afterward, image registration and segmentation were performed on all TMAs to obtain colocalized nuclei with respective labels. Nucleus centroid and a set of boundary points were the readouts in this process that are further loaded to feature computation modules to complete the feature matrix construction.
Article Snippet:
Techniques: Staining